
What Affects Metabolism? 8 Factors

Like our fingerprints, our metabolisms are uniquely our own—some people may have slower metabolisms and show signs of fatigue, and others may have metabolisms that work at the speed of light to provide enough energy for a three-hour strength training session.
While your metabolic health can be largely influenced by your genes, like your fingerprints, your muscle mass, hormones, diet, age, sleep, stress levels, and environment may also affect your metabolic functions.
In this article, we’ll deep dive into what affects metabolism and explore what you can do to improve your metabolic health.
#1 Genes
From largely determining our heights to governing the foods we prefer, genetics play a large role in our lives. It only makes sense that genes greatly impact our metabolisms, as well.
When it comes to metabolism, melanocortin-4 receptor (MC4R) is one gene that especially stands out.[1]
In recent years, scientists have discovered that people who have a rare type of MC4R are less likely to be overweight with body fat than people who lack this version. This correlation indicates that MC4R may help determine our metabolic rates.
Kinase suppressor of Ras 2 (KSR2) is another gene that, when altered, may affect metabolism.[2]
Studies suggest that KSR2 mutations may predispose people to the following:
- An increased risk of obesity
- Increased insulin resistance
- A cellular inability to properly process glucose
Genetics also play a role in hormones and muscle mass, two factors that, as we’ll see, help determine a person’s metabolic health.











